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Structure of 4655-10-1
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4'-Chloro-[1,1'-biphenyl]-3-carboxylic acid features a chlorinated aryl group paired with a carboxylic acid functionality, enabling direct incorporation into pharmaceutical scaffolds. The para-chloro substitution enhances electron-withdrawing character and improves metabolic stability. This compound serves as a key intermediate in the synthesis of bioactive molecules requiring rigid, planar aromatic systems.
4'-Chloro-[1,1'-biphenyl]-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of biaryl scaffolds via standard coupling reactions. Its carboxylic acid functionality facilitates direct derivatization into amides, esters, or acyl chlorides, while the ortho-chloro substituent provides a handle for subsequent cross-coupling or electrophilic functionalization. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: