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CS-W001157 4
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4-(2-Bromoethyl)tetrahydropyran

  • CAS No. 4677-20-7

  • Cat. No. CS-M3430
  • Molecule weight193.08
  • Purity≥97%
  • MDL No.MFCD09800414

*For research and further manufacturing use only, not for direct human use.

4-(2-Bromoethyl)tetrahydropyran|CS-M3430

Structure of 4677-20-7

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General Information

  • CAS No. 4677-20-7
  • Cat. No. CS-M3430
  • Purity ≥97%
  • MDL No. MFCD09800414
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃BrO
  • Molecular Weight 193.08
  • Synonym(s) 4-(2-Bromoethyl)tetrahydro-2H-pyran; 4-(2-Bromoethyl)tetrahydropyran; 4-(2-broMoethyl)oxane
  • SMILES BrCCC1CCOCC1

Description

4-(2-Bromoethyl)tetrahydropyran is a versatile synthetic intermediate featuring a bromoalkyl handle tethered to a tetrahydropyran ring. This configuration enables site-specific functionalization in complex molecule assembly, particularly in the construction of glycoside analogs and bioactive heterocycles. The pendant bromide offers high reactivity under nucleophilic substitution conditions, while the cyclic ether stabilizes reactive intermediates. Its bench-stable nature facilitates handling in multi-step syntheses without decomposition.

Application

4-(2-Bromoethyl)tetrahydropyran serves as a versatile bifunctional building block in synthetic organic chemistry, combining a reactive bromoalkyl handle with a stable tetrahydropyran ring. It facilitates efficient nucleophilic substitution reactions, enabling rapid access to ether-linked scaffolds and functionalized heterocycles. The compound exhibits excellent bench stability and compatibility with diverse reaction conditions, making it well-suited for applications in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   2.198
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   2

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