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CS-W001157 4
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N-Pentylboronic acid

  • CAS No. 4737-50-2

  • Cat. No. CS-W018820
  • Molecule weight115.97
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-Pentylboronic acid|CS-W018820

Structure of 4737-50-2

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General Information

  • CAS No. 4737-50-2
  • Cat. No. CS-W018820
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃BO₂
  • Molecular Weight 115.97
  • Synonym(s) 1-Pentaneboronic Acid (contains varying amounts of Anhydride)
  • SMILES CCCCCB(O)O

Description

N-Pentylboronic acid offers a stable, moisture-tolerant boronate handle for Suzuki-Miyaura cross-coupling reactions. The linear pentyl chain enhances solubility in organic media while maintaining reactivity under standard conditions. This boronate moiety integrates cleanly into complex molecular architectures without requiring protective group manipulation.

Application

N-Pentylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient C–C bond formation under mild conditions. Its stability, ease of handling, and compatibility with diverse functional groups make it ideal for constructing complex molecular architectures in medicinal chemistry and materials science.

Synthesis

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      N-Pentylboronic acid|CS-W018820
      4737-50-2

    References

    • French; Fine Journal of the American Chemical Society, 1938 , vol. 60, p. 352 Full Text View citing articles Show Details Snyder; Kuck; Johnson Journal of the American Chemical Society, 1938 , vol. 60, p. 110
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      N-Pentylboronic acid|CS-W018820
      4737-50-2

    References

    • Priestley; De Lucca, Indawati; Ghavimi, Bahman; Erickson-Viitanen, Susan; Decicco, Carl P. Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 21 p. 3199 - 3202
  • Route3
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      68498-84-0
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      693-25-4
    • ~%
    • In-stock
      N-Pentylboronic acid|CS-W018820
      4737-50-2

    References

    • Laurent,J.-P. Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1961 , vol. 253, p. 1812 - 1814

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.6494
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   4

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