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Structure of 475250-46-5
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This boronate moiety features a sterically hindered tetramethyl-1,3,2-dioxaborolane ring paired with a para-trifluoromethylbenzyl substituent, delivering enhanced stability and solubility in organic media. The electron-deficient trifluoromethyl group improves reactivity in cross-coupling processes, enabling efficient C–C bond formation under standard conditions.
4,4,5,5-Tetramethyl-2-(4-(trifluoromethyl)benzyl)-1,3,2-dioxaborolane serves as a stable, bench-ready boron building block for Suzuki-Miyaura cross-coupling reactions. The trifluoromethylbenzyl group imparts enhanced lipophilicity and metabolic stability, making it valuable for constructing biologically relevant scaffolds. Its tetramethyl-substituted dioxaborolane core ensures high chemical stability, excellent functional group tolerance, and compatibility with standard coupling conditions across diverse substrates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: