(S)-4-Hydroxypiperidin-2-one

Name: (S)-4-Hydroxypiperidin-2-one
Brand: ChemScene
Availability: InStock
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CAS No. 476014-92-3
Cat. No. CS-W021175
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 476014-92-3

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Description

(S)-4-Hydroxypiperidin-2-one is a chiral heterocyclic scaffold featuring a hydroxyl group at the C4 position and a carbonyl at C2, enabling direct functionalization in asymmetric synthesis. This bench-stable motif integrates readily into bioactive molecules, offering enhanced solubility and hydrogen-bonding capacity for medicinal chemistry applications.

Application

(S)-4-Hydroxypiperidin-2-one serves as a versatile chiral building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. Its well-defined stereochemistry and functional group tolerance facilitate direct derivatization via alkylation, acylation, or reductive amination. The molecule's bench-stable nature and compatibility with standard purification methods make it ideal for multi-step synthesis workflows targeting peptidomimetics and kinase inhibitors.

General Information

CAS No. 476014-92-3
Cat. No. CS-W021175
Purity ≥95%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₉NO₂
Molecular Weight 115.13
Synonym(s) 4-(S)-HYDROXY-2-PIPERIDINONE
SMILES O=C1NCC[C@H](O)C1

Computational Chemistry Data

TPSA 49.33
LogP -0.7427
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(S)-4-Hydroxypiperidin-2-one

CAS No. 476014-92-3

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