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Structure of 4771-49-7
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6-Methylindole-3-carboxyaldehyde features a sterically hindered indole core with a reactive aldehyde group at the 3-position, enabling direct conjugation in bioconjugation and heterocyclic synthesis. The methyl substituent enhances electron density at the aromatic ring, improving stability under standard conditions while maintaining high reactivity toward nucleophiles. This compound serves as a key building block for functionalized indole derivatives in medicinal chemistry and materials science.
6-Methylindole-3-carboxyaldehyde serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-aldehyde functionality enables efficient aldol condensations, reductive aminations, and Ugi-type reactions, while the methyl group enhances metabolic stability. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic campaigns in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: