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Structure of 4774-14-5
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2,6-Dichloropyrazine is a heterocyclic building block featuring two chlorine substituents at the 2 and 6 positions of the pyrazine ring. This electron-deficient scaffold enables efficient coupling in cross-coupling reactions and serves as a key structural motif in pharmaceutical intermediates and functional materials.
2,6-Dichloropyrazine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient functionalization at the pyrazine core. Its dichloro substitution pattern facilitates palladium-catalyzed cross-coupling reactions, including Suzuki-Miyaura and Buchwald-Hartwig aminations, with high regioselectivity. The compound exhibits excellent bench stability and compatibility with common protecting groups, making it ideal for multi-step synthetic sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: