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Structure of 478968-51-3
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This pyrazole derivative features a conjugated keto-carboxylic acid motif, enabling direct integration into bioactive scaffolds. The planar heterocyclic core supports robust hydrogen bonding and dipolar interactions, while the electron-deficient ring facilitates nucleophilic substitution at the 4-position. Ideal for medicinal chemistry campaigns requiring polar, rigid intermediates with defined spatial orientation and enhanced solubility profiles under standard conditions.
3-Oxo-2,3-dihydro-1H-pyrazole-4-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrazole-based heterocycles via standard functional group transformations. Its carboxylic acid and enone functionalities support diverse coupling reactions, cyclizations, and derivatization pathways under mild conditions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns targeting bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: