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Tert-butyl 4-(3-methoxy-3-oxopropanoyl)piperidine-1-carboxylate

  • CAS No. 479630-02-9

  • Cat. No. CS-0492208
  • Purity≥98%
  • MDL No.MFCD11974569

*For research and further manufacturing use only, not for direct human use.

Tert-butyl 4-(3-methoxy-3-oxopropanoyl)piperidine-1-carboxylate|CS-0492208

Structure of 479630-02-9

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General Information

  • CAS No. 479630-02-9
  • Cat. No. CS-0492208
  • Purity ≥98%
  • MDL No. MFCD11974569
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₃NO₅
  • Molecular Weight 285.34
  • Synonym(s) 1-Boc-beta-oxo-4-piperidinepropanoic acid methyl ester
  • SMILES COC(=O)CC(=O)C1CCN(CC1)C(=O)OC(C)(C)C

Synthesis

  • Route1

    References

    • Raimundo, Brian C.; Oslob, Johan D.; Braisted, Andrew C.; Hyde, Jennifer; McDowell, Robert S.; Randal, Mike; Waal, Nathan D.; Wilkinson, Jennifer; Yu, Chul H.; Arkin, Michelle R. Journal of Medicinal Chemistry, 2004 , vol. 47, # 12 p. 3111 - 3130
  • Route2
    • null|null
      67-56-1
    • tert-Butyl 4-(2,2-dimethyl-4,6-dioxo-1,3-dioxane-5-carbonyl)piperidine-1-carboxylate|CS-0132692
      1336874-02-2
    • ~%
    • Tert-butyl 4-(3-methoxy-3-oxopropanoyl)piperidine-1-carboxylate|CS-0492208
      479630-02-9

    References

    • IRM LLC; GAO, Wenqi; LAU, Thomas; PAN, Shifeng; PHILLIPS, Dean Paul; WANG, Xia; YANG, Yang Patent: WO2012/82947 A1, 2012 ; Location in patent: Page/Page column 62 ; WO 2012/082947 A1
  • Route3

    References

    • IRM LLC; GAO, Wenqi; LAU, Thomas; PAN, Shifeng; PHILLIPS, Dean Paul; WANG, Xia; YANG, Yang Patent: WO2012/82947 A1, 2012 ; WO 2012/082947 A1

Safety Information

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GHS Pictogram : N/A
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Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   72.91
  • LogP   1.7657
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   3

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