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Structure of 480450-04-2
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This silyl-protected carboxylic acid features a sterically hindered tert-butyl group flanking a diphenylsilyl ether moiety, enabling selective protection of alcohols in complex molecule synthesis. The robust silyl anchor withstands standard deprotection conditions while maintaining stability under basic and nucleophilic environments.
3-((tert-Butyldiphenylsilyl)oxy)-2,2-dimethylpropanoic acid serves as a robust silyl-protected hydroxyl precursor in complex molecule synthesis. The tert-butyldiphenylsilyl group provides excellent stability under a range of reaction conditions while enabling selective deprotection with fluoride sources. Its sterically hindered ester moiety enhances resistance to nucleophilic attack, facilitating purification and handling. This compound functions effectively in multi-step sequences requiring orthogonal protection strategies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: