Boc-Thr(Me)-OH

Name: Boc-Thr(Me)-OH
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 48068-25-3
Cat. No. CS-W019436
Molecule weight233.26
Purity≥97%
MDL No.MFCD00076990

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 48068-25-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 48068-25-3
Cat. No. CS-W019436
Purity ≥97%
MDL No. MFCD00076990
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₉NO₅
Molecular Weight 233.26
Synonym(s) None
SMILES C(=O)(OC(C)(C)C)N[C@@H]([C@H](OC)C)C(=O)O

Description

Boc-Thr(Me)-OH is a protected threonine derivative featuring a tert-butoxycarbonyl group and a methylated hydroxyl moiety, enabling stable incorporation into peptide chains. This configuration enhances solubility and simplifies purification during synthetic workflows. The methyl substitution reduces side reactions at the β-hydroxyl position, offering improved control in solid-phase peptide synthesis.

Application

Boc-Thr(Me)-OH serves as a readily handleable, bench-stable amino acid building block for peptide synthesis, enabling efficient incorporation of N-tert-butyloxycarbonyl-protected threonine with a methylated side chain. Its functional group tolerance and predictable reactivity facilitate robust coupling protocols and orthogonal deprotection strategies in complex peptide and heterocyclic scaffold assembly.

Synthesis

Route1
- In-stock
  
  4144-02-9
- In-stock
  
  24424-99-5
- ~94%
- In-stock
  
  48068-25-3
References
- PFIZER INC.; BAGAL, Sharanjeet Kaur; BROWN, Alan Daniel; KEMP, Mark Ian; KLUTE, Wolfgang; MARRON, Brian Edward; MILLER, Duncan Charles; SKERRATT, Sarah Elizabeth; SUTO, Mark J.; WEST, Christopher William; MALET SANZ, Laia Patent: WO2013/114250 A1, 2013 ; Location in patent: Page/Page column 161 ;
Route2
- In-stock
  
  2592-18-9
- 74-88-4
- ~%
- In-stock
  
  48068-25-3
References
- Chen,F.M.F.; Benoiton,N.L. Journal of Organic Chemistry, 1979 , vol. 44, p. 2299 - 2300

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 84.86
LogP 0.9992
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 4

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Threonine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Key Words

Boc-Thr(Me)-OH sigmaBoc-Thr(Me)-OH manufacturerBoc-Thr(Me)-OH priceBoc-Thr(Me)-OH structureBoc-Thr(Me)-OH SDSbuy Boc-Thr(Me)-OHBoc-Thr(Me)-OH supplierBoc-Thr(Me)-OH usesBoc-Thr(Me)-OH molecular weightprice of Boc-Thr(Me)-OHBoc-Thr(Me)-OH chemical name formula of Boc-Thr(Me)-OH

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Boc-Thr(Me)-OH

CAS No. 48068-25-3

Recommended Products