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Structure of 486-73-7
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Isoquinoline-1-carboxylic acid was used in the preparation of 4-cyano-3-ethoxy-1-hydroxy-5,6,7,8-tetrahydroisoquinoline.
Isoquinioline-1-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through standard coupling and functionalization reactions. Its carboxylic acid group facilitates amide bond formation and derivatization under mild conditions, while the fused quinoline core offers inherent stability and π-system compatibility for further transformations. The compound exhibits good bench stability and is amenable to purification via recrystallization or chromatography, making it well-suited for use in multi-step synthetic sequences targeting bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: