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Structure of 486422-04-2
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N,N-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide is a bench-stable boronate reagent featuring a sulfonamide handle and electron-rich boronate moiety. This compound integrates readily into Suzuki-Miyaura coupling reactions under mild conditions, enabling efficient C–C bond formation with aryl halides. The tetramethyl-substituted dioxaborolane enhances stability and solubility in common organic solvents.
N,N-Dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide serves as a stable, bench-ready boronate building block for Suzuki-Miyaura coupling reactions. The sulfonamide group provides excellent solubility and functional group tolerance, enabling efficient late-stage diversification in medicinal chemistry. Its tetramethylboronate moiety facilitates reliable cross-coupling under mild conditions, making it ideal for constructing biaryl scaffolds in drug discovery and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302
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Precautionary Statements : P264-P270-P330-P501
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Lot numbers can be found on the outside label of a product: