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CS-W001157 4
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3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine

  • CAS No. 486460-20-2

  • Cat. No. CS-0171529
  • Molecule weight188.11
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine|CS-0171529

Structure of 486460-20-2

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General Information

  • CAS No. 486460-20-2
  • Cat. No. CS-0171529
  • Purity ≥97%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃F₃N₄
  • Molecular Weight 188.11
  • Synonym(s) 3-(TRIFLUOROMETHYL)-1,2,4-TRIAZOLO[4,3-A]-PYRAZINE
  • SMILES C1=CN2C(=NN=C2C(F)(F)F)C=N1

Synthesis

  • Route1
    • null|null
      1447800-65-8
    • ~89%
    • 3-(Trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyrazine|CS-0171529
      486460-20-2

    References

    • Nitlikar, Lakshmikant H.; Darandale, Sunil N.; Shinde, Devanand B. Letters in Organic Chemistry, 2013 , vol. 10, # 5 p. 348 - 352
  • Route2

    References

    • SUNSHINE LAKE PHARMA CO., LTD.; ZHANG, Jiancun; ZHANG, Yingjun; ZHANG, Weihong; LIU, Bing; ZHANG, Jiquan; LIU, Jinlei; ZHANG, Lu Patent: WO2013/71697 A1, 2013 ; Location in patent: Paragraph 00199 ;
  • Route3

    References

    • MERCK and CO., INC. Patent: WO2004/58266 A1, 2004 ; Location in patent: Page/Page column 87 ; WO 2004/058266 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   43.08
  • LogP   1.1431
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

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