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CS-W001157 4
Total: USD 88.00

2-(4-(Hydroxymethyl)phenyl)ethanol

  • CAS No. 4866-85-7

  • Cat. No. CS-0157536
  • Purity≥98%
  • MDL No.MFCD22690919

*For research and further manufacturing use only, not for direct human use.

2-(4-(Hydroxymethyl)phenyl)ethanol|CS-0157536

Structure of 4866-85-7

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General Information

  • CAS No. 4866-85-7
  • Cat. No. CS-0157536
  • Purity ≥98%
  • MDL No. MFCD22690919
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₂O₂
  • Molecular Weight 152.19
  • Synonym(s) None
  • SMILES C1=C(C=CC(=C1)CO)CCO

Description

2-(4-(Hydroxymethyl)phenyl)ethanol features a phenolic hydroxyl group and a terminal primary alcohol, enabling dual functionalization in synthetic transformations. This bifunctional scaffold supports conjugation strategies in polymer chemistry and bioconjugation workflows. The molecule exhibits good solubility in polar solvents and stability under standard bench conditions.

Application

2-(4-(Hydroxymethyl)phenyl)ethanol serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive scaffolds through standard functional group manipulations. Its phenolic hydroxyl and primary alcohol functionalities offer orthogonal reactivity for derivatization, while its stability under routine reaction conditions facilitates purification and scale-up in synthetic workflows.

Synthesis

  • Route1

    References

    • Pechlivanidis, Zissis; Hopf, Henning; Ernst, Ludger European Journal of Organic Chemistry, 2009 , # 2 p. 223 - 237
  • Route2

    References

    • Hoover, Jessica M.; Stahl, Shannon S. Journal of the American Chemical Society, 2011 , vol. 133, # 42 p. 16901 - 16910

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   0.7137
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   3

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