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Structure of 487-69-4
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This 2,4-dihydroxy-6-methylbenzaldehyde features a methyl-substituted aromatic ring flanked by two hydroxyl groups and a formyl functionality, delivering enhanced solubility and stability under standard conditions. The ortho-hydroxyl arrangement facilitates chelation in metal coordination, while the para-positioned methyl group imparts steric protection to the aldehyde. This combination enables efficient incorporation into synthetic scaffolds for bioactive molecule development.
2,4-Dihydroxy-6-methylbenzaldehyde serves as a versatile building block in the synthesis of bioactive heterocycles and natural product analogs. Its ortho-dihydroxy motif enables reliable metal chelation and oxidation to quinones, while the aldehyde group facilitates condensation reactions with amines, hydrazines, and nucleophiles under mild conditions. The methyl substituent enhances solubility and metabolic stability in downstream scaffolds, making it valuable for medicinal chemistry campaigns requiring bench-stable, functionalized aromatic intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: