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Structure of 489431-66-5
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2,5-Dibromo-3-methoxypyrazine is a brominated pyrazine derivative featuring two electrophilic bromine substituents and a methoxy group at the 3-position. This configuration enables selective coupling reactions in synthetic applications, particularly in cross-coupling protocols where controlled reactivity and stability under standard conditions are required.
2,5-Dibromo-3-methoxypyrazine serves as a versatile building block for the synthesis of substituted pyrazine derivatives via palladium-catalyzed cross-coupling reactions. The bromo groups enable sequential functionalization at C2 and C5 positions, while the methoxy group provides a stable, electron-donating handle compatible with standard synthetic workflows. Its bench-stable crystalline form facilitates handling and purification, making it well-suited for medicinal chemistry and materials science applications requiring precise heterocyclic diversification.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: