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CS-W001157 4
Total: USD 88.00

3-Amino-5-bromothiophene-2-carboxamide

  • CAS No. 494833-79-3

  • Cat. No. CS-0067550
  • Molecule weight221.08
  • Purity95+%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Amino-5-bromothiophene-2-carboxamide|CS-0067550

Structure of 494833-79-3

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General Information

  • CAS No. 494833-79-3
  • Cat. No. CS-0067550
  • Purity 95+%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BrN₂OS
  • Molecular Weight 221.08
  • Synonym(s) None
  • SMILES O=C(C1=C(N)C=C(Br)S1)N

Synthesis

  • Route1
    • tert-Butyl (5-bromo-2-carbamoylthiophen-3-yl)carbamate|CS-0666054
      494833-78-2
    • ~%
    • 3-Amino-5-bromothiophene-2-carboxamide|CS-0067550
      494833-79-3

    References

    • ASTRAZENECA AB; ASTRAZENECA UK LIMITED Patent: WO2004/63186 A1, 2004 ; Location in patent: Page 37 ; WO 2004/063186 A1
  • Route2

    References

    • Takeda Pharmaceutical Company Limited Patent: EP2540728 A1, 2013 ; Location in patent: Page/Page column 44 ;
  • Route3
    • 3-Amino-5-bromothiophene-2-carboxylic acid|CS-0373001
      1244027-57-3
    • ~79%
    • 3-Amino-5-bromothiophene-2-carboxamide|CS-0067550
      494833-79-3

    References

    • TAKEDA PHARMACEUTICAL COMPANY LIMITED; OGURO, Yuya; KURASAWA, Osamu Patent: WO2010/101302 A1, 2010 ; Location in patent: Page/Page column 131-132 ; WO 2010/101302 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   69.11
  • LogP   1.1917
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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