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CS-W001157 4
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4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid

  • CAS No. 495-77-2

  • Cat. No. CS-0091593
  • Molecule weight167.17
  • Purity≥97%
  • MDL No.MFCD00222266

*For research and further manufacturing use only, not for direct human use.

4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid|CS-0091593

Structure of 495-77-2

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General Information

  • CAS No. 495-77-2
  • Cat. No. CS-0091593
  • Purity ≥97%
  • MDL No. MFCD00222266
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉N₃O₂
  • Molecular Weight 167.17
  • Synonym(s) 4,5,6,7-Tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acid
  • SMILES O=C(O)C1NCC(NC=N2)=C2C1

Description

4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid delivers a rigid, nitrogen-rich heterocyclic core with enhanced solubility and metabolic stability. This scaffold integrates readily into medicinal chemistry libraries, offering a polar, hydrogen-bond-capable moiety ideal for modulating target affinity and pharmacokinetic profiles in CNS-directed drug discovery.

Application

4,5,6,7-Tetrahydro-3H-imidazo[4,5-c]pyridine-6-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and process development. Its fused bicyclic core exhibits favorable bench stability and functional group tolerance, enabling direct derivatization via amide coupling, reduction, or electrophilic substitution. The carboxylic acid moiety facilitates conjugation and salt formation, enhancing solubility and bioavailability in target-oriented synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   78.01
  • LogP   -0.4914
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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