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Structure of 49633-25-2
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3-Isopropyl-1H-pyrazole features a sterically hindered pyrazole core with enhanced solubility in organic media. This bench-stable heterocycle serves as a robust scaffold for medicinal chemistry, integrating readily into bioactive molecules via functionalization at the 1- and 3-positions.
3-Isopropyl-1H-pyrazole serves as a versatile heterocyclic building block in medicinal chemistry and process development, offering enhanced solubility and metabolic stability compared to simpler alkyl-substituted analogs. Its pyrazole core facilitates hydrogen bonding and π–stacking interactions in target binding pockets, while the isopropyl group provides steric bulk and improved lipophilicity profile. The compound exhibits excellent bench stability, enabling straightforward handling and purification via standard distillation or column chromatography. It functions effectively in transition-metal-catalyzed coupling reactions and serves as a key scaffold for constructing bioactive molecules across diverse therapeutic areas.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: