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Structure of 49678-02-6
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trans-p-Chlorocinnamaldehyde features a conjugated enone system with a para-chloro substituent, delivering enhanced electrophilicity and stability under standard bench conditions. This electron-deficient alkene integrates readily into Michael addition cascades and serves as a key scaffold in the synthesis of bioactive heterocycles and pharmaceutical intermediates.
trans-p-Chlorocinnamaldehyde serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of substituted styrenes and heterocycles via Michael additions, Mannich reactions, and Wittig-type transformations. Its conjugated enal system exhibits predictable reactivity with nucleophiles and electrophiles, while the para-chloro substituent enhances electronic modulation and facilitates downstream functionalization. Bench-stable and readily purified by distillation or chromatography, it functions reliably in multi-step syntheses requiring controlled regioselectivity and thermal stability.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H317-H319
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Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501
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Lot numbers can be found on the outside label of a product: