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Structure of 49679-45-0
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Ethyl 3-chloroquinoxaline-2-carboxylate features a chlorinated quinoxaline core with a carboxylate ester handle, enabling direct integration into C–H functionalization and cross-coupling cascades. The electron-deficient heterocycle pairs effectively with nucleophiles, while the ethyl ester facilitates derivatization under mild conditions. This scaffold delivers robust reactivity in transition-metal-catalyzed transformations.
Ethyl 3-chloroquinoxaline-2-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to quinoxaline-based scaffolds. The chloro substituent at the 3-position facilitates nucleophilic aromatic substitution, while the ester group supports further functionalization. Its stability and compatibility with standard coupling reactions make it well-suited for medicinal chemistry campaigns and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: