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Structure of 497959-29-2
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(2-Chloro-4-fluorophenyl)hydrazine hydrochloride is a bench-stable hydrazine derivative featuring a strategically positioned chloro and fluoro substituent on the phenyl ring. This electronic tuning enhances reactivity in C–N bond-forming transformations, enabling efficient coupling with carbonyl electrophiles. The hydrochloride salt improves solubility and handling stability, streamlining integration into synthetic workflows for heterocyclic and pharmaceutical intermediates.
(2-Chloro-4-fluorophenyl)hydrazine hydrochloride serves as a key building block in the synthesis of heterocyclic scaffolds, particularly for triazoles and imidazoles via cyclization reactions. Its well-defined reactivity enables efficient coupling with carbonyl derivatives and electrophiles under mild conditions. The compound exhibits good bench stability and facilitates straightforward purification, making it suitable for scalable medicinal chemistry campaigns and API intermediate development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: