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Structure of 500298-30-6
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1-Bromo-3-methoxy-2-nitrobenzene features a strategically positioned bromine atom flanked by electron-withdrawing nitro and electron-donating methoxy groups, enabling selective cross-coupling reactions. This ortho-disubstituted aromatic scaffold offers enhanced reactivity in palladium-catalyzed transformations while maintaining stability under standard conditions.
1-Bromo-3-methoxy-2-nitrobenzene serves as a versatile building block in cross-coupling reactions, enabling efficient construction of biaryl and heteroaryl scaffolds. The bromine moiety facilitates palladium-catalyzed coupling under standard conditions, while the ortho-nitro and meta-methoxy groups provide orthogonal reactivity and enhanced solubility. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for iterative synthesis in medicinal chemistry and materials science applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: