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Structure of 501653-39-0
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Methyl 4-(3-methoxyphenyl)-2,4-dioxobutanoate features a conjugated β-keto ester scaffold flanked by a para-methoxyphenyl group, enabling efficient enolization and nucleophilic reactivity. This bench-stable intermediate integrates readily into multicomponent condensations and serves as a key building block for heterocyclic frameworks in medicinal chemistry.
Methyl 4-(3-methoxyphenyl)-2,4-dioxobutanoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted pyran and chromene scaffolds. Its α,β-unsaturated β-ketoester functionality facilitates Michael additions, condensations, and cyclizations under mild conditions. The molecule exhibits good bench stability and simplifies purification due to its crystalline nature, making it well-suited for iterative synthesis in medicinal chemistry and natural product derivatization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: