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Structure of 5018-38-2
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4,6-Dichloro-5-methoxypyrimidine serves as a pivotal building block in heterocyclic synthesis, featuring two electrophilic chlorine sites flanking a methoxy-substituted pyrimidine core. This configuration enables selective substitution reactions under mild conditions, facilitating the construction of complex pharmaceutical intermediates and functionalized nucleosides with high regiocontrol.
4,6-Dichloro-5-methoxypyrimidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyrimidine-based scaffolds through nucleophilic substitution. The dichloro functionality offers orthogonal reactivity for sequential functionalization, while the methoxy group enhances solubility and modulates electronic properties. Its bench-stable solid form facilitates handling and purification, making it well-suited for scalable synthesis of API intermediates and heterocyclic libraries.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H318
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Precautionary Statements : P264-P270-P280-P330-P501
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Lot numbers can be found on the outside label of a product: