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Structure of 5028-32-0
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1-Methyl-1H-imidazo[4,5-c]pyridine features a rigid, planar heteroaromatic core combining imidazole and pyridine moieties, delivering enhanced electron density and stability. This scaffold integrates readily into medicinal chemistry libraries, serving as a key building block for bioactive compounds with improved metabolic resilience and target affinity.
1-Methyl-1H-imidazo[4,5-c]pyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient construction of bioactive scaffolds. Its rigid, planar structure provides favorable π-stacking and hydrogen-bonding interactions in target binding sites. The molecule exhibits excellent bench stability and functional group tolerance, facilitating downstream derivatization via electrophilic substitution or transition-metal-catalyzed coupling reactions. Widely employed in the synthesis of kinase inhibitors and CNS-targeted compounds, it functions as a key core motif in drug discovery campaigns requiring enhanced metabolic stability and membrane permeability.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: