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Structure of 5043-14-1
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7-Bromo-2-naphthoic acid is a bench-stable, moisture-tolerant naphthalene derivative bearing a bromine substituent at the 7-position and a carboxylic acid group at the 2-position. This combination enables direct functionalization in cross-coupling reactions and facilitates conjugation to biomolecules or polymers via amide bond formation.
7-Bromo-2-naphthoic acid serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the naphthalene core for pharmaceutical and materials applications. Its bromine substituent facilitates palladium-catalyzed cross-coupling reactions, while the carboxylic acid group supports derivatization via esterification, amidation, or decarboxylative transformations. The compound exhibits good bench stability and is readily purified by recrystallization, making it well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: