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Structure of 50562-19-1
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This trifluoromethylated aryl alcohol features a fluorinated phenyl ring and a hydroxyl-bearing carbon center, delivering enhanced stability and lipophilicity. The electron-withdrawing trifluoromethyl group modulates reactivity, while the pendant hydroxyl enables downstream functionalization. Ideal for synthetic intermediates in medicinal chemistry and materials science applications.
2,2,2-Trifluoro-1-(4-fluorophenyl)ethan-1-ol serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated aromatic scaffolds via standard functional group interconversions. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the benzylic alcohol functionality facilitates derivatization through oxidation, protection, or coupling reactions. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis campaigns in drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H227-H315-H319-H335
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Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501
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Lot numbers can be found on the outside label of a product: