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CS-W001157 4
Total: USD 88.00

2,2,2-Trifluoro-1-(4-fluorophenyl)ethan-1-ol

  • CAS No. 50562-19-1

  • Cat. No. CS-0120240
  • Purity≥95%
  • MDL No.MFCD00615801
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

2,2,2-Trifluoro-1-(4-fluorophenyl)ethan-1-ol|CS-0120240

Structure of 50562-19-1

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Description

This trifluoromethylated aryl alcohol features a fluorinated phenyl ring and a hydroxyl-bearing carbon center, delivering enhanced stability and lipophilicity. The electron-withdrawing trifluoromethyl group modulates reactivity, while the pendant hydroxyl enables downstream functionalization. Ideal for synthetic intermediates in medicinal chemistry and materials science applications.

Application

2,2,2-Trifluoro-1-(4-fluorophenyl)ethan-1-ol serves as a valuable building block in medicinal chemistry, enabling the construction of fluorinated aromatic scaffolds via standard functional group interconversions. Its trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the benzylic alcohol functionality facilitates derivatization through oxidation, protection, or coupling reactions. The compound exhibits good bench stability and is compatible with common purification methods, making it well-suited for iterative synthesis campaigns in drug discovery.

General Information

  • CAS No. 50562-19-1
  • Cat. No. CS-0120240
  • Purity ≥95%
  • MDL No. MFCD00615801
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆F₄O
  • Molecular Weight 194.13
  • Synonym(s) 2,2,2-TRIFLUORO-1-(4-FLUOROPHENYL)ETHANOL
  • SMILES OC(C(F)(F)F)C1=CC=C(F)C=C1

Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.4214
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501

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