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CS-W001157 4
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Methyl piperidine-3-carboxylate

  • CAS No. 50585-89-2

  • Cat. No. CS-W005063
  • Molecule weight143.18
  • Purity≥95%
  • MDL No.MFCD00797850

*For research and further manufacturing use only, not for direct human use.

Methyl piperidine-3-carboxylate|CS-W005063

Structure of 50585-89-2

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General Information

  • CAS No. 50585-89-2
  • Cat. No. CS-W005063
  • Purity ≥95%
  • MDL No. MFCD00797850
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₂
  • Molecular Weight 143.18
  • Synonym(s) PIPERIDINE-3-CARBOXYLIC ACID METHYL ESTER
  • SMILES COC(C1CCCNC1)=O

Description

Methyl piperidine-3-carboxylate is a bench-stable, moisture-tolerant heterocyclic ester featuring a tertiary amine center. This compound integrates readily into synthetic routes requiring nitrogen-directed functionalization, offering enhanced solubility in polar organic solvents and compatibility with standard coupling conditions.

Synthesis

  • Route1
    • Methyl nicotinate, ≥99%|CS-1269198
      93-60-7
    • ~43%
    • In-stock
      Methyl piperidine-3-carboxylate|CS-W005063
      50585-89-2

    References

    • Yoon,U.C.; Quillen,S.L.; Mariano,P.S. Journal of the American Chemical Society, 1983 , vol. 105, p. 1204
  • Route2
    • null|null
      67-56-1
    • In-stock
      Nipecotic acid|CS-W020556
      498-95-3
    • ~98%
    • In-stock
      Methyl piperidine-3-carboxylate|CS-W005063
      50585-89-2

    References

    • Vanlaer, Sofie; Voet, Arnout; Gielens, Constant; De Maeyer, Marc; Compernolle, Frans European Journal of Organic Chemistry, 2009 , # 5 p. 643 - 654
  • Route3
    • null|null
      1083159-14-1
    • ~%
    • In-stock
      Methyl piperidine-3-carboxylate|CS-W005063
      50585-89-2

    References

    • Chakrapani, Harinath; Maciag, Anna E.; Citro, Michael L.; Keefer, Larry K.; Saavedra, Joseph E. Organic Letters, 2008 , vol. 10, # 22 p. 5155 - 5158

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   0.159
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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