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Structure of 50597-88-1
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2-Iodo-1-methoxy-4-methylbenzene features a strategically positioned iodine atom flanked by electron-donating methoxy and methyl groups, enhancing its reactivity in palladium-catalyzed cross-coupling reactions. The methoxy substituent improves solubility, while the methyl group provides steric stabilization, enabling efficient transformations under standard conditions.
2-Iodo-1-methoxy-4-methylbenzene serves as a versatile aryl iodide building block in palladium-catalyzed cross-coupling reactions, enabling efficient C–C bond formation under standard Suzuki, Stille, and Negishi conditions. The methoxy and methyl groups provide orthogonal functional handles for further derivatization, while the iodide facilitates reliable coupling with minimal side reactivity. Its bench-stable nature and ease of purification make it well-suited for iterative synthesis workflows in medicinal chemistry and materials science.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: