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CS-W001157 4
Total: USD 88.00

6-Chloro-3-oxo-2,3-dihydropyridazine-4-carboxylic acid

  • CAS No. 50681-26-0

  • Cat. No. CS-0072094
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

6-Chloro-3-oxo-2,3-dihydropyridazine-4-carboxylic acid|CS-0072094

Structure of 50681-26-0

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Description

6-Chloro-3-oxo-2,3-dihydropyridazine-4-carboxylic acid features a chlorinated pyridazine core with a conjugated ketone and carboxylic acid moiety, enabling direct incorporation into bioactive heterocycles. The electron-deficient ring system supports efficient coupling reactions, while the bench-stable functionality facilitates use in synthetic medicinal chemistry workflows.

Application

6-Chloro-3-oxo-2,3-dihydropyridazine-4-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling efficient access to pyridazine-based scaffolds prevalent in medicinal chemistry. Its functional group pattern—chloro, oxo, and carboxylic acid—supports diverse transformations including nucleophilic substitution, amide formation, and cyclization reactions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic campaigns and API intermediate development.

General Information

  • CAS No. 50681-26-0
  • Cat. No. CS-0072094
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃ClN₂O₃
  • Molecular Weight 174.54
  • Synonym(s) 6-Chloro-3-hydroxypyridazine-4-carboxylic acid
  • SMILES O=C1C(C(O)=O)=CC(Cl)=NN1

Computational Chemistry Data

  • TPSA   83.05
  • LogP   0.1215
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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