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Structure of 50823-87-5
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4-Methoxy-3-(trifluoromethyl)benzaldehyde features a trifluoromethyl group that enhances electron-withdrawal and metabolic stability, while the para-methoxy substituent provides electron donation and improved solubility. This dual functionalization enables efficient coupling in cross-coupling reactions and facilitates incorporation into bioactive scaffolds under standard conditions.
4-Methoxy-3-(trifluoromethyl)benzaldehyde serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to substituted benzimidazoles, heterocycles, and bioactive scaffolds. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the methoxy and aldehyde functionalities provide orthogonal handles for derivatization. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis and high-throughput screening workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: