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Structure of 50901-43-4
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Pyridazin-4-ylmethanol features a pyridazinone core with a primary alcohol handle, enabling direct functionalization in synthetic sequences. This bench-stable scaffold integrates readily into bioactive molecule design, particularly where nitrogen-rich heterocycles enhance target affinity. The hydroxymethyl group facilitates derivatization under mild conditions, supporting efficient access to diverse analogs.
Pyridazin-4-ylmethanol serves as a versatile building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds through straightforward functionalization. Its benzylic alcohol functionality facilitates oxidation to the aldehyde or carboxylic acid, and it participates reliably in coupling reactions with amines, halides, and boronic acids. The pyridazinone core exhibits favorable metabolic stability and hydrogen-bonding capacity, making it suitable for target-directed synthesis. Bench-stable and readily purified by silica gel chromatography, it functions effectively in standard synthetic workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: