3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide

Name: 3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 50978-45-5
Cat. No. CS-0106913
Purity≥97%
MDL No.MFCD23380208

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide|CS-0106913

Structure of 50978-45-5

Size

Price

Quantity

* Please select Quantity before adding items.

Description

This electron-deficient heterocyclic aldehyde features a fused benzo[d]isothiazole core with both carbonyl and sulfone functionalities, enabling direct incorporation into complex molecular architectures. The 1,1-dioxide group enhances stability and polarity, facilitating handling under standard conditions while maintaining reactivity for conjugate additions and transition-metal-catalyzed couplings.

Application

3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide serves as a versatile building block in heterocyclic synthesis, enabling efficient access to complex sulfonamide-containing scaffolds. Its electrophilic carbonyl and sulfonyl groups facilitate nucleophilic addition and condensation reactions under mild conditions. The molecule exhibits good bench stability and compatibility with diverse functional groups, making it well-suited for iterative synthesis strategies in medicinal chemistry and process development workflows.

General Information

CAS No. 50978-45-5
Cat. No. CS-0106913
Purity ≥97%
MDL No. MFCD23380208
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₅NO₄S
Molecular Weight 211.19
Synonym(s) N-Formylsaccharin
SMILES O=CN(C(C1=C2C=CC=C1)=O)S2(=O)=O

Computational Chemistry Data

TPSA 71.52
LogP -0.0125
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Benzothiazole compounds

Chemical Synthesis Synthetic Reagents C-C Bond Formation Carbon Monoxide Surrogate Reagents

Chemical Synthesis Synthetic Reagents C-X(Non-Halogen) Bond Formation Formylation

Key Words

50978-45-5 sigma50978-45-5 manufacturer50978-45-5 price50978-45-5 structure50978-45-5 SDSbuy 50978-45-550978-45-5 supplier50978-45-5 uses50978-45-5 molecular weightprice of 50978-45-550978-45-5 chemical name formula of 50978-45-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3-Oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide

CAS No. 50978-45-5

Recommended Products