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Structure of 51171-02-9
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Methyl 3-bromopyrazine-2-carboxylate is a halogenated pyrazine derivative featuring a bromine atom at the 3-position and a methyl ester at the 2-position. This electron-deficient heterocycle integrates readily into cross-coupling reactions, enabling efficient access to functionalized pyrazine scaffolds under palladium-catalyzed conditions. The ester group enhances solubility and facilitates downstream derivatization.
Methyl 3-bromopyrazine-2-carboxylate serves as a versatile building block in medicinal chemistry and heterocyclic synthesis. The bromine at the C3 position enables palladium-catalyzed cross-coupling reactions, while the ester group facilitates further functionalization or hydrolysis to the carboxylic acid. Its stability under standard reaction conditions and compatibility with diverse coupling partners make it a practical choice for constructing complex pyrazine-based scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: