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Structure of 51269-82-0
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5-Chloronicotinonitrile features a chlorine atom at the 5-position of a pyridine ring, paired with a nitrile group at the 3-position. This electron-deficient heterocycle serves as a key building block in agrochemical and pharmaceutical synthesis, offering enhanced reactivity for nucleophilic substitution and coupling reactions under standard conditions.
5-Chloronicotinonitrile serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of heterocyclic scaffolds and functionalized pharmaceutical intermediates. Its dual functionality—electrophilic chlorine and electron-withdrawing nitrile group—facilitates nucleophilic substitution, palladium-catalyzed coupling reactions, and regioselective derivatization. The compound exhibits excellent bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis campaigns in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: