2,3-Dimethoxyphenol

Name: 2,3-Dimethoxyphenol
Brand: ChemScene
Availability: InStock
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CAS No. 5150-42-5
Cat. No. CS-0150321
Purity≥98%
MDL No.MFCD00008366

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Structure of 5150-42-5

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Description

2,3-Dimethoxyphenol features two methoxy groups positioned ortho to each other on a phenolic backbone, enhancing solubility and stabilizing the aromatic system. This configuration imparts strong electron-donating character, making it valuable in synthesis of complex natural products and functional materials. The compound exhibits bench-stable handling under standard conditions and integrates readily into oxidative coupling reactions.

Application

2,3-Dimethoxyphenol serves as a valuable building block in synthetic organic chemistry, enabling access to substituted aromatic scaffolds via standard electrophilic and transition-metal-catalyzed coupling reactions. Its ortho-dimethoxy substitution pattern provides enhanced stability and facilitates selective functionalization, while the phenolic hydroxyl group allows for derivatization or protection under mild conditions. The compound’s bench-stable nature and compatibility with diverse reaction conditions make it a practical choice for medicinal chemistry and natural product synthesis workflows.

General Information

CAS No. 5150-42-5
Cat. No. CS-0150321
Purity ≥98%
MDL No. MFCD00008366
Storage RT, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀O₃
Molecular Weight 154.16
Synonym(s) Phenol, 2,3-dimethoxy- (8CI)(9CI)
SMILES COC1=CC=CC(=C1OC)O

Computational Chemistry Data

TPSA 38.69
LogP 1.4094
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Other Classifications

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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2,3-Dimethoxyphenol

CAS No. 5150-42-5

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