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Structure of 51647-90-6
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7-Hydroxyimidazo[1,2-a]pyrimidin-5(8H)-one is a heterocyclic scaffold featuring a hydroxyl group at the 7-position and a lactam carbonyl at C5, conferring enhanced solubility and hydrogen-bonding capacity. This structure integrates readily into bioactive molecule design, particularly in kinase inhibitors and nucleoside analogs, where its polarity supports target engagement and metabolic stability under standard conditions.
7-Hydroxyimidazo[1,2-a]pyrimidin-5(8H)-one serves as a versatile heterocyclic building block for medicinal chemistry campaigns, enabling efficient access to imidazopyrimidine scaffolds prevalent in kinase inhibitors and antiviral agents. Its hydroxyl group provides a handle for derivatization via esterification, etherification, or metal-catalyzed coupling, while the core framework exhibits bench stability and compatibility with standard purification methods. This compound functions effectively in multistep syntheses requiring regioselective functionalization and demonstrates predictable reactivity in common transformation protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: