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CS-W001157 4
Total: USD 88.00

5-Iodoisophthalic acid

  • CAS No. 51839-16-8

  • Cat. No. CS-0169459
  • Purity≥98%
  • MDL No.MFCD12913553
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Iodoisophthalic acid|CS-0169459

Structure of 51839-16-8

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Description

5-Iodoisophthalic acid features a rigid aromatic core with two carboxylic acid groups flanking a para-iodo substituent, enabling precise functionalization in cross-coupling reactions. This configuration supports efficient derivatization for bioconjugation and materials synthesis under standard conditions.

Application

5-Iodoisophthalic acid serves as a versatile building block for metal-catalyzed cross-coupling reactions, enabling efficient access to functionalized aromatic scaffolds. Its iodine substituent facilitates palladium-catalyzed coupling with boronic acids, stannanes, and amines, while the two carboxylic acid groups provide sites for derivatization, salt formation, or incorporation into polymers and bioactive molecules. Bench-stable and readily purified by recrystallization, it functions effectively in standard synthetic workflows requiring ortho-functionalized isophthalate motifs.

General Information

  • CAS No. 51839-16-8
  • Cat. No. CS-0169459
  • Purity ≥98%
  • MDL No. MFCD12913553
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅IO₄
  • Molecular Weight 292.03
  • Synonym(s) None
  • SMILES O=C(O)C1=CC(I)=CC(=C1)C(=O)O

Computational Chemistry Data

  • TPSA   74.6
  • LogP   1.6876
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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