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CS-W001157 4
Total: USD 88.00

(2-Fluorobenzyl)hydrazine

  • CAS No. 51859-98-4

  • Cat. No. CS-0053072
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(2-Fluorobenzyl)hydrazine|CS-0053072

Structure of 51859-98-4

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General Information

  • CAS No. 51859-98-4
  • Cat. No. CS-0053072
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉FN₂
  • Molecular Weight 140.16
  • Synonym(s) hydrazine, [(2-fluorophenyl)methyl]-
  • SMILES NNCC1=C(F)C=CC=C1

Description

(2-Fluorobenzyl)hydrazine is a bench-stable hydrazine derivative featuring a fluorinated benzyl moiety, enabling selective functionalization in synthetic pathways. The electron-withdrawing fluorine substituent enhances reactivity while maintaining compatibility with diverse reaction conditions. This compound integrates readily into heterocyclic systems and serves as a key intermediate in medicinal chemistry applications requiring precise nitrogen incorporation.

Application

(2-Fluorobenzyl)hydrazine serves as a versatile building block in medicinal chemistry, enabling the construction of hydrazone-linked scaffolds through selective condensation with aldehydes and ketones. Its fluorinated aromatic ring enhances metabolic stability and modulates electronic properties, while the hydrazine moiety facilitates downstream transformations such as cyclization to heterocycles or oxidative cleavage. The compound exhibits good bench stability and is compatible with standard purification methods, making it suitable for high-throughput synthesis workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   0.789
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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