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(±)-α-Tocopherol nicotinate

  • CAS No. 51898-34-1

  • Cat. No. CS-0144088
  • Molecule weight535.80
  • Purity≥98%
  • MDL No.MFCD03548047

*For research and further manufacturing use only, not for direct human use.

(±)-α-Tocopherol nicotinate|CS-0144088

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General Information

  • CAS No. 51898-34-1
  • Cat. No. CS-0144088
  • Purity ≥98%
  • MDL No. MFCD03548047
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₅H₅₃NO₃
  • Molecular Weight 535.80
  • Synonym(s) rel-Vitamin E Nicotinate
  • SMILES CC1=C2C(CC[C@](C)(O2)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)=C(C(OC(C3=CN=CC=C3)=O)=C1C)C

Description

Esterifying the phenolic hydroxyl of RRR-α-tocopherol with nicotinic acid yields a lipid-soluble derivative, (±)-α-Tocopherol nicotinate (CAS 51898-34-1), enhancing bioavailability for cellular antioxidant defense systems.

Application

(±)-α-Tocopherol nicotinate (CAS 51898-34-1) drives metabolic pathway analysis in rat models by enhancing antioxidant enzyme activity and stabilizing lipid membranes under oxidative stress. It supports redox homeostasis. Researchers use this compound to evaluate its role in systemic vitamin E delivery and cellular energy metabolism.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   48.42
  • LogP   9.74886
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   14

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