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CS-W001157 4
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1,4,6,7-Tetrahydropyrano[4,3-c]pyrazole-3-carboxylic acid

  • CAS No. 518990-20-0

  • Cat. No. CS-W021285
  • Molecule weight168.15
  • Purity≥98%
  • MDL No.MFCD10566785

*For research and further manufacturing use only, not for direct human use.

1,4,6,7-Tetrahydropyrano[4,3-c]pyrazole-3-carboxylic acid|CS-W021285

Structure of 518990-20-0

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General Information

  • CAS No. 518990-20-0
  • Cat. No. CS-W021285
  • Purity ≥98%
  • MDL No. MFCD10566785
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈N₂O₃
  • Molecular Weight 168.15
  • Synonym(s) Pyrano[4,3-c]pyrazole-3-carboxylic acid, 1,4,6,7-tetrahydro- (9CI)
  • SMILES O=C(C1=NNC2=C1COCC2)O

Description

This tetrahydropyranopyrazole carboxylic acid integrates a fused polycyclic scaffold with defined stereochemistry, offering enhanced metabolic stability and tailored solubility. The carboxylic acid functionality enables direct conjugation or salt formation, while the electron-rich heterocycle supports diverse coupling reactions under standard conditions.

Application

1,4,6,7-Tetrahydropyrano[4,3-c]pyrazole-3-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and synthetic organic applications. Its fused pyranopyrazole core provides structural rigidity and enhanced metabolic stability, while the carboxylic acid functionality enables facile derivatization via amide coupling, esterification, or salt formation. The compound exhibits good bench stability and functional group tolerance, facilitating integration into multi-step syntheses of bioactive molecules and API intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.21
  • LogP   0.1806
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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