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Structure of 5194-32-1
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2-Methylpyrimidine-5-carboxylic acid features a pyrimidine core functionalized with a methyl group at the 2-position and a carboxylic acid at the 5-position, offering enhanced solubility and reactivity in synthetic transformations. This scaffold integrates readily into bioactive molecule design, particularly in medicinal chemistry applications where heterocyclic stability and polarity are critical.
2-Methylpyrimidine-5-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization reactions. Its pyrimidine core provides structural rigidity and hydrogen-bonding capacity, while the carboxylic acid group facilitates amide formation, esterification, and derivatization under mild conditions. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses requiring good functional group tolerance and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: