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Structure of 51940-63-7
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Ethyl 6-chloropyrimidine-4-carboxylate features a chlorinated pyrimidine core with a strategically positioned ester group, enabling direct incorporation into heterocyclic scaffolds. The electron-deficient ring facilitates nucleophilic substitution reactions under mild conditions, while the ethyl ester serves as a versatile handle for further functionalization in medicinal chemistry and agrochemical synthesis.
Ethyl 6-chloropyrimidine-4-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to pyrimidine-based scaffolds through nucleophilic substitution and cross-coupling reactions. The chloro group at the C6 position exhibits high reactivity toward amines, thiols, and organometallic reagents, while the ester functionality supports further transformations. Its bench-stable nature and compatibility with standard purification methods make it well-suited for iterative medicinal chemistry campaigns and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: