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Structure of 52201-01-1
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4-(Trifluoromethyl)benzenesulfonyl fluoride delivers a highly electrophilic sulfonyl group flanked by a strong electron-withdrawing trifluoromethyl moiety, enabling efficient sulfonation of nucleophiles under mild conditions. This bench-stable reagent features enhanced reactivity and selectivity in synthetic transformations.
4-(Trifluoromethyl)benzenesulfonyl fluoride serves as a versatile sulfonylating agent in synthetic organic chemistry, enabling efficient introduction of the trifluoromethylsulfonyl group under mild conditions. Its high reactivity facilitates nucleophilic substitution with alcohols, amines, and thiols, forming stable sulfonate esters, amides, and thioethers. The compound exhibits excellent bench stability and compatibility with diverse functional groups, making it a practical choice for constructing sulfonamide-based pharmaceutical intermediates and bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H312-H314-H332-H335
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Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P330+P331-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P330-P362+P364-P363-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: