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Structure of 52414-97-8
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1-Bromo-3-methyl-2-nitrobenzene features a strategically positioned bromine atom adjacent to a methyl group and flanked by a nitro substituent, enabling selective cross-coupling reactions. This electron-deficient aryl halide exhibits enhanced reactivity in palladium-catalyzed transformations, offering efficient access to complex substituted arenes under standard conditions.
1-Bromo-3-methyl-2-nitrobenzene serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its reactive aryl bromide moiety. The ortho-nitro group provides strong electron-withdrawing character, enhancing electrophilicity for nucleophilic aromatic substitution. Its bench-stable nature and compatibility with standard functional group transformations make it ideal for constructing complex heterocyclic scaffolds and multi-functionalized aromatic systems.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: