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Structure of 52545-13-8
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4-Methoxypyridin-2(1H)-one features a pyridinone core with a methoxy group at the 4-position, conferring enhanced solubility and metabolic stability. This scaffold serves as a key building block in medicinal chemistry, particularly for designing kinase inhibitors and bioactive heterocycles due to its ability to form hydrogen bonds and engage in π–stacking interactions.
4-Methoxypyridin-2(1H)-one serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to pyridone-based scaffolds. Its amide-like reactivity at the carbonyl position facilitates nucleophilic substitution and coupling reactions under mild conditions. The methoxy group enhances solubility and modulates electronic properties, while the compound exhibits good bench stability and compatibility with common functional groups, simplifying purification and integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: