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Structure of 52601-23-7
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Quinuclidine-2-carboxylic acid hydrochloride features a rigid, bicyclic quinuclidine core with a carboxylic acid group at the 2-position, delivering enhanced solubility and stability. The hydrochloride salt form ensures excellent handling properties and facilitates use in medicinal chemistry applications.
Quinuclidine-2-carboxylic acid hydrochloride serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through its rigid bicyclic framework and orthogonal functionalization. The carboxylic acid group facilitates direct amidation, esterification, or metal-catalyzed coupling reactions, while the protonated quinuclidine nitrogen enhances solubility and modulates basicity. This compound exhibits excellent bench stability, simplifies purification via salt formation, and functions reliably in standard peptide and small-molecule synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: