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CS-W001157 4
Total: USD 88.00

4-(γ-Pyridyl)butanol

  • CAS No. 5264-15-3

  • Cat. No. CS-0028752
  • Molecule weightNone
  • Purity≥97%
  • MDL No.MFCD03265696

*For research and further manufacturing use only, not for direct human use.

4-(γ-Pyridyl)butanol|CS-0028752

Structure of 5264-15-3

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General Information

  • CAS No. 5264-15-3
  • Cat. No. CS-0028752
  • Purity ≥97%
  • MDL No. MFCD03265696
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₃NO
  • Molecular Weight None
  • Synonym(s) 4-Pyridinebutanol
  • SMILES OCCCCC1=CC=NC=C1

Description

4-(γ-Pyridyl)butanol integrates a pyridyl heterocycle with a primary alcohol handle, enabling direct functionalization in cross-coupling and conjugation workflows. This bench-stable, moisture-tolerant reagent features a linear aliphatic chain that enhances solubility in polar organic media, facilitating efficient derivatization in synthetic and materials applications.

Application

4-(γ-Pyridyl)butanol serves as a versatile building block in synthetic organic chemistry, enabling the construction of heterocyclic scaffolds and functionalized alkyl chains. Its pyridyl group offers moderate basicity and π-electron density, facilitating metal-catalyzed coupling reactions and electrophilic substitutions. The terminal primary alcohol allows for straightforward derivatization via esterification, etherification, or oxidation to aldehyde/carboxylic acid. Bench-stable and readily purified by distillation or chromatography, it functions effectively in multistep syntheses requiring orthogonal functional group handling.

Synthesis

  • Route1

    References

    • Capuano, Ben; Crosby, Ian T.; Lloyd, Edward J.; Podloucka, Anna; Taylor, David A. Australian Journal of Chemistry, 2008 , vol. 61, # 12 p. 930 - 940
  • Route2
    • null|null
      84200-10-2
    • ~87%
    • In-stock
      4-(γ-Pyridyl)butanol|CS-0028752
      5264-15-3

    References

    • Mayer, Joachim M.; Testa, Bernard Helvetica Chimica Acta, 1982 , vol. 65, # 6 p. 1868 - 1884
  • Route3
    • null|null
      1120-87-2
    • ~%
    • In-stock
      4-(γ-Pyridyl)butanol|CS-0028752
      5264-15-3

    References

    • Lin, Peter; Parikh, Mamta; Lo, Jane-Ling; Yang, Yi Tien; Cheng, Kang; Smith, Roy G; Fisher, Michael H; Wyvratt, Matthew J; Goulet, Mark T Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 8 p. 1077 - 1080

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.3966
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   4

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